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Acetaminophen and oxycodone are a mixture medicine used to relieve moderate to severe pain. Acetaminophen and oxycodone can also be used for purposes unlisted during this medication guide. Acetaminophen and oxycodone contain an opioid medicine and should be habit-forming. Acetaminophen and oxycodone can also be used for purposes unlisted during this medication guide. You should not use this medicine if you're allergic to acetaminophen or oxycodone, or if you have: Severe asthma or breathing problems; or a blockage in your stomach or intestines. Tell your doctor if you've got ever had: § breathing problems, sleep apnea; § liver disease; § a drug or alcohol addiction; § kidney disease; § a head injury or seizures; § urination problems; or § Problems along with your thyroid, pancreas, or gallbladder. If you use opioid medicine while you're pregnant, your baby c...